CPT45385

How Much Does a Colonoscopy With Polyp Removal Cost in Missouri?

Colonoscopy w/lesion removal

$1,446Hospital outpatient total2026 Medicare, physician + facility

Under 2026 Medicare rates, a colonoscopy with polyp removal costs about $1,446 in total at a hospital outpatient department or about $880 at an ambulatory surgery center, counting both the physician and the facility (national rates). The physician's own fee in Missouri averages $218, from $215 to $221 across 3 Medicare localities.

Hospital payments are wage-adjusted by locality, so the ZIP changes the numbers.
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Missouri Medicare physician rate (2026)

-5.6% vs national

Average of 3 localities. Office range $453.48–$484.01.

Missouri (Hospital)
$218.46
Facility physician fee
Private plan est.
$614–$945
~130–200% of Medicare
Cash / self-pay est.
$378–$708
~80–150% of Medicare

What the whole procedure costs

The rate above is the physician’s fee on its own. The facility bills separately, and for most procedures the facility is the larger half of the bill. These are 2026 national Medicare amounts.

Surgery center, total
$880
$223 physician + $657 facility
Physician fee alone
$223
Only 15% of the hospital total

Choosing a surgery center over a hospital saves about $566 on the Medicare allowed amount for colonoscopy with polyp removal. Ask whether your procedure can be done at an ambulatory surgery center.

This is Medicare's separate payment to the facility on top of the physician's fee. Medicare allowed amounts are not what an uninsured patient is charged, and not a quote. Private plans typically allow more.

Your ZIP in Missouri

Enter a ZIP code to see which Missouri locality covers you: metro St. Louis, metro Kansas City, or rest-of-state areas like Springfield, Columbia, Joplin, and the Bootheel.

What colonoscopy with polyp removal costs at hospitals near you

Everything above is a national average. The hospital you pick in Missouri moves the bill more than anything else you control.

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Rates for your ZIP, 5 named hospitals with CMS ratings, the add-on codes, and the scheduler script.

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What these numbers are

Every figure on this page is a 2026 Medicare allowed amount: the physician line comes from the Physician Fee Schedule adjusted by geographic practice-cost indices, and the facility totals come from the CMS hospital outpatient (OPPS) and ambulatory surgery center rates. None of them is a hospital chargemaster price, your insurer's contracted rate, or a quote. Anesthesia, pathology, imaging reads and follow-up care are billed under their own codes when they apply, and an inpatient stay is paid a different way again. In Missouri the office and hospital physician lines for this CPT differ by $253.79.

National vs Missouri

National office$500.01
National hospital (physician)$223.45
Missouri vs national6% below the national office rate of $500.01

Where Missouri ranks for this CPT

Rank (lowest physician fee first)#17 of 51
Lowest stateArkansas ($444.65)
Highest stateAlaska ($588.56)

CPT 45385 by Missouri locality

LocalityOffice
metropolitan st. louis$484.01
metropolitan kansas city$479.25
rest of missouri$453.48

PE GPCI ranges from 0.862 to 0.952 in Missouri. That index is why the same CPT is not one price statewide.

Colonoscopy With Polyp Removal and how Missouri is priced

Missouri is a three-locality state: metropolitan St. Louis and metropolitan Kansas City are each priced separately, and everywhere else falls into a rest-of-state locality with lower geographic adjustments. Both metro localities approve higher amounts than outstate Missouri, and the Kansas City locality applies only to the Missouri side of that metro, since the Kansas side prices under Kansas's statewide locality. Springfield, Columbia, and the rural counties all share rest-of-state factors. The metro-versus-outstate gap is the main pricing story here.

St. Louis and Kansas City hold the state's academic medical centers and most of its specialty depth, drawing patients from far beyond Missouri's borders, including southern Illinois and eastern Kansas. Outstate Missouri is served by regional hubs in Springfield, Columbia, and Cape Girardeau, with the Ozarks and Bootheel among the harder places to reach specialty care. Rural hospital viability has been a persistent concern across the state.

This procedure: This colonoscopy code means the physician found one or more polyps and removed them using a snare, a thin wire loop that lassoes the polyp and cuts it free, often with cauterizing current. Snare removal is the standard technique for larger polyps and is the step that gives colonoscopy its cancer-preventing power, since removing precancerous polyps stops them from progressing. The patient experience is unchanged from any colonoscopy: prep, IV sedation, a 20 to 45 minute procedure, and same-day discharge.

What Is Colonoscopy With Polyp Removal?

This colonoscopy code means the physician found one or more polyps and removed them using a snare, a thin wire loop that lassoes the polyp and cuts it free, often with cauterizing current. Snare removal is the standard technique for larger polyps and is the step that gives colonoscopy its cancer-preventing power, since removing precancerous polyps stops them from progressing. The patient experience is unchanged from any colonoscopy: prep, IV sedation, a 20 to 45 minute procedure, and same-day discharge.

What Affects the Cost

  • –Every removed polyp goes to pathology in its own container, and each container is a separate lab charge.
  • –The physician fee for snare polypectomy is the highest of the common colonoscopy codes, above both biopsy (45380) and diagnostic (45378).
  • –Facility setting remains the biggest overall cost lever, with hospitals charging far more than endoscopy centers.
  • –Separately billed anesthesia adds its own professional fee.
  • –Large or complex polyps may require advanced removal techniques or clips to close the site, which can add device and procedure charges.
  • –Finding polyps shortens your recommended interval to the next colonoscopy, pulling that future cost closer.

Questions to Ask Before Booking

  • 1.If polyps are removed during my screening, will the procedure still be billed with the preventive modifier at no cost share to me?
  • 2.What will the pathology lab charge per polyp, and is that lab in network?
  • 3.For Medicare: what percentage coinsurance applies to polyp removal during a screening this year?
  • 4.If you find a large polyp needing a special technique or clips, how does the cost change?
  • 5.How soon will I need my next colonoscopy if polyps are found, and will that one count as screening or surveillance for coverage?

Colonoscopy With Polyp Removal in Missouri: questions

Under 2026 Medicare rates, a colonoscopy with polyp removal costs about $1,446 in total at a hospital outpatient department or about $880 at an ambulatory surgery center, counting both the physician and the facility (national rates). The physician's own fee in Missouri averages $218, from $215 to $221 across 3 Medicare localities. Enter a ZIP for the exact Missouri locality.

Yes. CMS splits Missouri into 3 payment localities. For this CPT the office physician fee spans $30.53 from the lowest to highest locality. Enter a ZIP code to see which Missouri locality covers you: metro St. Louis, metro Kansas City, or rest-of-state areas like Springfield, Columbia, Joplin, and the Bootheel.

After the Part B deductible, coinsurance is usually 20% of the allowed amount: about $94 for the office physician line or $44 for the hospital physician line in Missouri. Medigap may cover that 20%. This is not the hospital facility fee.

No. $218.46 is only the physician's share. Adding Medicare's facility payment brings the total to about $1,446 in a hospital outpatient department, or about $880 at an ambulatory surgery center. Anesthesia, pathology and other codes billed the same day are extra. Missouri ranks #17 of 51 states on the physician line (6% below the national office rate of $500.01).

Data source: 2026 Medicare Physician Fee Schedule (CMS PPRRVU26B, released March 2026). Conversion factor: $33.4009. Prices shown are Medicare allowed amounts for the physician service and may not match what you are billed. Private insurance and self-pay ranges, when shown, are labeled estimates (typical multiples of Medicare), not quotes. This site is an independent cost tool, not medical advice.