CPT45380

Colonoscopy With Biopsy Cost in New York

Colonoscopy and biopsy

$1,400Hospital outpatient total2026 Medicare, physician + facility
Hospital payments are wage-adjusted by locality, so the ZIP changes the numbers.
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New York Medicare physician rate (2026)

+10.6% vs national

Average of 5 localities. Office range $458.30–$565.57.

New York (Hospital)
$193.75
Facility physician fee
Private plan est.
$690–$1,062
~130–200% of Medicare
Cash / self-pay est.
$425–$796
~80–150% of Medicare

What the whole procedure costs

The rate above is the physician’s fee on its own. The facility bills separately, and for most procedures the facility is the larger half of the bill. These are 2026 national Medicare amounts.

Surgery centre, total
$834
$178 physician + $657 facility
Physician fee alone
$178
Only 13% of the hospital total

Choosing a surgery centre over a hospital saves about $566 on the Medicare allowed amount for colonoscopy with biopsy. Ask whether your procedure can be done at an ambulatory surgery centre.

This is Medicare's separate payment to the facility on top of the physician's fee. Medicare allowed amounts are not what an uninsured patient is charged, and not a quote. Private plans typically allow more.

Your ZIP in New York

New York's multiple localities make a ZIP-level check essential: compare Manhattan, Queens and the outer boroughs, Long Island, the Hudson Valley near Poughkeepsie, and upstate cities like Buffalo, Rochester, Syracuse, and Albany.

What colonoscopy with biopsy costs at hospitals near you

Everything above is a national average. The hospital you pick in New York moves the bill more than anything else you control.

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Rates for your ZIP, 5 named hospitals with CMS ratings, the add-on codes, and the scheduler script.

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What these numbers are

Every figure on this page is a 2026 Medicare allowed amount: the physician line comes from the Physician Fee Schedule adjusted by geographic practice-cost indices, and the facility totals come from the CMS hospital outpatient (OPPS) and ambulatory surgery centre rates. None of them is a hospital chargemaster price, your insurer's contracted rate, or a quote. Anesthesia, pathology, imaging reads and follow-up care are billed under their own codes when they apply, and an inpatient stay is paid a different way again. In New York the office and hospital physician lines for this CPT differ by $337.23.

National vs New York

National office$479.97
National hospital (physician)$177.69
New York vs national11% above the national office rate of $479.97

Where New York ranks for this CPT

Rank (lowest physician fee first)#47 of 51
Lowest stateArkansas ($423.81)
Highest stateAlaska ($554.38)

CPT 45380 by New York locality

LocalityOffice
nyc suburbs/long island$565.57
queens$557.30
manhattan$552.32
poughkpsie/n nyc suburbs$521.39
rest of new york$458.30

PE GPCI ranges from 0.950 to 1.189 in New York. That index is why the same CPT is not one price statewide.

Colonoscopy With Biopsy and how New York is priced

New York has one of the most complex locality maps in the country, with around five payment areas: Manhattan is its own locality, Queens is separately priced, the NYC suburbs and Long Island form another high-cost locality, the Poughkeepsie area has its own, and the rest of the state, including Buffalo, Rochester, Syracuse, and Albany, shares a distinctly lower-priced upstate locality. The spread between Manhattan and upstate adjustments is among the widest within any state. A knee MRI or office visit is approved at meaningfully different amounts in Manhattan, Mineola, and Rochester. Upstate New York prices closer to the Midwest than to the five boroughs.

New York City is a global medical capital with world-famous academic medical centers competing within blocks of each other, while upstate cities each center on their own regional academic hubs. Long Island and the lower Hudson Valley support dense suburban hospital markets of their own. The upstate-downstate divide runs through everything in New York health care, including what providers charge and what patients can access locally.

This procedure: This is a colonoscopy during which the physician passes small forceps through the scope to take one or more tissue samples, called cold biopsies, from the colon lining. It is used when the doctor sees inflammation, an unusual patch, or needs to test for conditions like microscopic colitis, which can only be diagnosed under a microscope. From the patient's perspective it is identical to any colonoscopy: prep the day before, IV sedation, a 20 to 45 minute exam, and home the same day.

What Is Colonoscopy With Biopsy?

This is a colonoscopy during which the physician passes small forceps through the scope to take one or more tissue samples, called cold biopsies, from the colon lining. It is used when the doctor sees inflammation, an unusual patch, or needs to test for conditions like microscopic colitis, which can only be diagnosed under a microscope. From the patient's perspective it is identical to any colonoscopy: prep the day before, IV sedation, a 20 to 45 minute exam, and home the same day.

What Affects the Cost

  • Every biopsy container sent to the lab is billed separately by pathology, and workups for conditions like microscopic colitis involve samples from multiple colon segments.
  • The physician fee for 45380 is higher than the diagnostic-only code 45378 because sampling was performed.
  • Facility choice between hospital outpatient and freestanding endoscopy center remains the largest single price driver.
  • Separate anesthesia billing applies when a dedicated provider administers sedation.
  • If a polyp is also removed by snare during the same exam, an additional code (45385) is billed alongside this one.

Questions to Ask Before Booking

  • 1.Was my colonoscopy ordered as a screening or for symptoms, and how will biopsies affect what I owe under my specific plan?
  • 2.How many specimen jars might be sent to pathology and what is the charge per jar?
  • 3.Is the pathology lab in my insurance network?
  • 4.If you also remove a polyp with a snare, will both procedure codes be billed and what does that total?
  • 5.For Medicare patients: what coinsurance applies this year when a screening turns into a biopsy?

Colonoscopy With Biopsy in New York: questions

The 2026 Medicare physician office rate for CPT 45380 averages $530.98 across 5 New York localities, from $458.30 in REST OF NEW YORK to $565.57 in NYC SUBURBS/LONG ISLAND. The hospital physician rate averages $193.75. Enter a ZIP for the exact locality.

Yes. CMS splits New York into 5 payment localities. For this CPT the office physician fee spans $107.27 from the lowest to highest locality. New York's multiple localities make a ZIP-level check essential: compare Manhattan, Queens and the outer boroughs, Long Island, the Hudson Valley near Poughkeepsie, and upstate cities like Buffalo, Rochester, Syracuse, and Albany.

After the Part B deductible, coinsurance is usually 20% of the allowed amount: about $106 for the office physician line or $39 for the hospital physician line in New York. Medigap may cover that 20%. This is not the hospital facility fee.

No. $530.98 is only the physician's share. Adding Medicare's facility payment brings the total to about $1,400 in a hospital outpatient department, or about $834 at an ambulatory surgery centre. Anesthesia, pathology and other codes billed the same day are extra. New York ranks #47 of 51 states on the physician line (11% above the national office rate of $479.97).

Data source: 2026 Medicare Physician Fee Schedule (CMS PPRRVU26B, released March 2026). Conversion factor: $33.4009. Prices shown are Medicare allowed amounts for the physician service and may not match what you are billed. Private insurance and self-pay ranges, when shown, are labeled estimates (typical multiples of Medicare), not quotes. This site is an independent cost tool, not medical advice.